A study of the relation of marijuana use to psychosocial disorders

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Int Rev Psychiatry. Clinical and psychophysiological effects of cannabis in long-term users.

A study of the relation of marijuana use to psychosocial disorders

CBT focuses on teaching skills relevant to quitting cannabis and to avoiding or coping with other problems that might interfere with good outcomes. An additional number of participants significantly reduce their use, but still a substantial proportion does not show evidence of progress. Harvey, W. Cannabis withdrawal among nontreatment-seeking adult cannabis users. Tennant, F. Several studies have linked marijuana use to increased risk for psychiatric disorders, including psychosis schizophrenia , depression, anxiety, and substance use disorders, but whether and to what extent it actually causes these conditions is not always easy to determine. First, lithium dosing during a 7-day residential episode was associated with good cannabis outcomes during the year following treatment without substantial safety or side effects concerns. Harshman, R. Wells, J. Journal of Neuroscience Research, 4 1 , American Journal of Psychiatry, 2 ,

The final trial in this series was conducted at 3 sites in the U. Notably, subgroup analyses found that interventions of more than four sessions delivered over longer than one month high intensity produced consistently improved outcomes particularly in terms of cannabis use frequency and severity of dependence in the short term as compared with low-intensity interventions.

In Levin, H.

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British Journal of Psychiatry, J Psychopharmacol. III Predictors of progression. Cannabinioid antagonist treatments paralleling the effective opioid antagonist model naltrexone also hold promise, however, the only cannabinoid antagonist evaluated to date, rimonabant, has concomitant adverse effects that make its use untenable.

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We use prospective data on treatment received for cannabis use disorders and a range of other diagnoses from the index admission until the end of Using logistic regression of prospective data, we studied associations between baseline characteristics and work and study status in Archives of General Psychiatry, 27 1 , AJDC, , Comprehensive Psychiatry, 20, Rapid advances in the neurobiology of cannabis and the cannabinoid system provide optimism that novel agonist- or antagonist-like compounds that indirectly alter CB1 receptor site functioning may be synthesized and show efficacy without adverse effects. Millman, R. Cannabis and cognitive functions: a prospective study.

References 1. Bupropion, clonidine, nefazodone, naltrexone, and divalproex have not shown robust effects across multiple measures that would suggest therapeutic efficacy, and in some cases have produced effects opposite of those desired.

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Pharmacological and psychosocial interventions for cannabisuse disorders